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Retatrutide

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GLP-3-RT is an investigational triple receptor agonist consisting of 39 amino acids that targets GLP-1, GIP, and glucagon receptors simultaneously. This compound is investigated in research for enhanced metabolic regulation and weight management through activation of three complementary metabolic pathways. The triple-agonist approach combines the glucose-dependent insulin secretion of GLP-1R, the incretin effects of GIPR, and the hepatic lipid metabolism modulation of GCGR, providing comprehensive metabolic support in experimental models exceeding the efficacy of dual or single-receptor agonists.


Areas of research include:

  • GLP-1, GIP, and glucagon receptor activity

  • Metabolic signaling pathways

  • Energy balance research

  • Receptor interaction studies

  • Incretin biology


Scientific Specifications:


Compound Name: GLP-3-RT (Triple GLP-1/GIP/Glucagon Receptor Agonist)

Type: Triple GLP-1/GIP/Glucagon Receptor Agonist

Amino Acid Count: 39 amino acids

Molecular Weight: ~4731.33 g/mol

CAS Number: 2381089-83-2

Form: Lyophilized powder


Research Context:

GLP-3-RT is commonly studied for its potential effects on:


Triple receptor agonism targeting GLP-1R, GIPR, and GCGR simultaneously

Enhanced weight management via combined and synergistic metabolic pathway activation

Glycemic control and glucose-dependent insulin modulation mechanisms

Hepatic lipid metabolism enhancement and energy expenditure modulation

Appetite suppression through complementary and redundant satiety mechanisms

Comparative efficacy assessment versus dual-receptor and single-receptor agonist approaches


Intended Use:

This product is intended strictly for laboratory research applications only by qualified scientific personnel. It is not approved for human or animal consumption, and may not be used in foods, drugs, supplements, cosmetics, or diagnostics.


Legal Disclaimer:

The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.


Terms of Sale:

By purchasing this product, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance.

For research use only.


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